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10 Best Bed Bug Sprays 2025 in the United States
#1
Winner
Ortho Home Defense Max Bed Bug, Flea and Tick Killer with Comfort Wand, Bed Bug Spray, Kills Bed Bug Eggs, Fleas and Ticks, 1 gal.
The Ortho Home Defense Max Bed Bug, Flea and Tick Killer is a versatile 1-gallon spray designed to tackle bed bugs, including their eggs, as well as fleas and ticks. One of its strong points is its effectiveness against even the toughest bed bugs, including those resistant to common treatments. The Comfort Wand that comes with it makes it easier to apply, especially in hard-to-reach places such as mattress seams and baseboards. This feature can be a significant advantage for those dealing with infestations in multiple areas of their home.
Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!#2
Eco Defense Bed Bug Killer - Bed Bug Spray & Dust Mite Spray - Natural Treatment - 16 oz
The Eco Defense Bed Bug Killer is a natural bed bug and dust mite spray intended to kill bed bugs at all life stages on contact. One of its major strengths is its use of natural and plant-based ingredients, such as Sodium Lauryl Sulfate and Geranium Oil, making it a safer option for households concerned about harmful chemicals. This can be especially beneficial for families with young children or pets. The non-staining formula allows users to apply it directly onto sheets and mattresses without worrying about damage, adding convenience and reassurance.
Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!#3
Hot Shot Ready-to-Use Bed Bug Killer Spray, Kills Bed Bugs and Bed Bug Eggs, Kills Fleas and Dust Mites, 32 Ounce
The Hot Shot Ready-to-Use Bed Bug Killer Spray is a versatile option designed to tackle bed bugs, bed bug eggs, fleas, and dust mites. Its water-based formula is beneficial as it is non-staining and leaves no odor, making it more pleasant for indoor use without worrying about lingering smells or marks. This spray is easy to use for spot treatments on mattresses, ensuring that all crucial areas are covered without the need for extensive spraying, although it should not be used on pets.
Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!Customer Highlights
A summary of real customer reviews to highlight what shoppers are saying!Top 10 Best Bed Bug Sprays 2025 in the United States
#1
Winner
10.0 score
Ortho Home Defense Max Bed Bug, Flea and Tick Killer with Comfort Wand, Bed Bug Spray, Kills Bed Bug Eggs, Fleas and Ticks, 1 gal.
Ortho Home Defense Max Bed Bug, Flea and Tick Killer with Comfort Wand, Bed Bug Spray, Kills Bed Bug Eggs, Fleas and Ticks, 1 gal.
Type of Spray: 1-gallon spray
Effectiveness: effective against bed bugs, fleas, ticks
Safety: use with care, spot treatment
Ease of Use: Comfort Wand for easy application
Odor: tick scent
Chosen by 1341 this week
Eco Defense Bed Bug Killer - Bed Bug Spray & Dust Mite Spray - Natural Treatment - 16 oz
Eco Defense Bed Bug Killer - Bed Bug Spray & Dust Mite Spray - Natural Treatment - 16 oz
Type of Spray: Spray
Effectiveness: Kills bed bugs on contact
Safety: Natural, safer for children or pets
Ease of Use: Easy to use, non-staining
Odor: Scent of geranium oil
Hot Shot Ready-to-Use Bed Bug Killer Spray, Kills Bed Bugs and Bed Bug Eggs, Kills Fleas and Dust Mites, 32 Ounce
Hot Shot Ready-to-Use Bed Bug Killer Spray, Kills Bed Bugs and Bed Bug Eggs, Kills Fleas and Dust Mites, 32 Ounce
Type of Spray: Bed Bug Killer Spray
Effectiveness: Effective against bed bugs, eggs, fleas
Safety: Non-staining, no odor, not for pets
Ease of Use: Easy for spot treatments
Odor: Odorless
BASF 31457 PT Alpine Flea & Bed Bug 14oz Pesticide Insecticide, White
BASF 31457 PT Alpine Flea & Bed Bug 14oz Pesticide Insecticide, White
Type of Spray: Aerosol
Effectiveness: Effective up to 3 weeks, targets eggs
Safety: Safe for public health and food
Ease of Use: Easy to apply
Odor: Minimal to no scent
Bed Bug Killer 16 oz EcoVenger by EcoRaider, 100% Kill Efficacy, Bedbugs & Mites, Kills Eggs & The Resistant, Lasting Protection, USDA BIO-Certified, Plant Extract Based & Non-Toxic, Child & Pet Safe
Bed Bug Killer 16 oz EcoVenger by EcoRaider, 100% Kill Efficacy, Bedbugs & Mites, Kills Eggs & The Resistant, Lasting Protection, USDA BIO-Certified, Plant Extract Based & Non-Toxic, Child & Pet Safe
Type of Spray: spray
Effectiveness: 100% efficacy in killing bed bugs
Safety: non-toxic, safe for children and pets
Ease of Use: sprayed directly on mattresses and springs
Odor: Cedarwood
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Hot Shot Bed Bug Killer Aerosol, Bed Bug Treatment, 17.5 oz
Hot Shot Bed Bug Killer Aerosol, Bed Bug Treatment, 17.5 oz
Type of Spray: Aerosol
Effectiveness: Controls bed bugs for 3 weeks
Safety: Handle with care, follow instructions
Ease of Use: Straightforward to use
Odor: No unpleasant odor
Hygea Natural Extra Strength Bed Bug & Mite Natural Travel Spray,TSA Approved Size, Child & Pet-Friendly, Stain & Odor Free, for Hotel, Suitcase, Backpack, Shoes, 66% Stronger Natural Formula(3oz)
Hygea Natural Extra Strength Bed Bug & Mite Natural Travel Spray,TSA Approved Size, Child & Pet-Friendly, Stain & Odor Free, for Hotel, Suitcase, Backpack, Shoes, 66% Stronger Natural Formula(3oz)
Type of Spray: Spray
Effectiveness: Kills bugs on contact
Safety: Child and pet-friendly
Ease of Use: Guide included
Odor: Odorless
MGK Bedlam Plus® | Fast-Acting Bed Bug Spray Aerosol | Insecticide Spray | for Indoor Use on Mattresses, Wood Furniture and Carpets | 17 Ounce Can
MGK Bedlam Plus® | Fast-Acting Bed Bug Spray Aerosol | Insecticide Spray | for Indoor Use on Mattresses, Wood Furniture and Carpets | 17 Ounce Can
Type of Spray: Aerosol
Effectiveness: Reduces bed bug egg hatch
Safety: Follow label instructions carefully
Ease of Use: Ready-to-use, no mixing required
Odor: Unscented
Harris 5 Minute Bed Bug Killer, Odorless & Non Staining Formula (128oz)
Harris 5 Minute Bed Bug Killer, Odorless & Non Staining Formula (128oz)
Type of Spray: Spray
Effectiveness: 5-minute kill, residual up to month
Safety: EPA registered
Ease of Use: Non-staining, odorless
Odor: Odorless
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Buying Guide for the Best Bed Bug Sprays
Choosing the right bed bug spray can be a daunting task, but with the right knowledge, you can make an informed decision that best suits your needs. Bed bug sprays are essential for effectively eliminating bed bugs and preventing their return. When selecting a bed bug spray, it's important to consider various factors such as the type of spray, its effectiveness, safety, and ease of use. Understanding these key specifications will help you choose the best product for your situation.Type of SprayBed bug sprays come in different types, including contact sprays, residual sprays, and natural sprays. Contact sprays kill bed bugs on contact and are ideal for immediate results. Residual sprays leave a lasting effect, killing bed bugs over time and preventing re-infestation. Natural sprays use plant-based ingredients and are safer for use around children and pets. Choose a contact spray for quick results, a residual spray for long-term protection, or a natural spray if you prefer a non-toxic option.
EffectivenessThe effectiveness of a bed bug spray is crucial in ensuring that it eliminates bed bugs and prevents their return. Look for sprays that are proven to kill bed bugs at all life stages, including eggs, nymphs, and adults. Some sprays are specifically formulated to target resistant strains of bed bugs. Check for customer reviews and scientific studies to gauge the effectiveness of the spray. If you have a severe infestation, opt for a highly effective spray that targets all life stages.
SafetySafety is an important consideration, especially if you have children, pets, or sensitive individuals in your household. Some bed bug sprays contain harsh chemicals that can be harmful if inhaled or ingested. Look for sprays that are labeled as safe for indoor use and have low toxicity levels. Natural and organic sprays are generally safer options. Always follow the manufacturer's instructions and safety guidelines when using the spray. If safety is a top priority, choose a natural or low-toxicity spray.
Ease of UseThe ease of use of a bed bug spray can affect how effectively you can treat an infestation. Sprays come in various forms, such as aerosol cans, pump sprays, and ready-to-use bottles. Aerosol cans are convenient for reaching tight spaces, while pump sprays offer more control over the application. Ready-to-use bottles are straightforward and require no mixing. Consider your comfort level and the specific areas you need to treat when choosing a spray. If you need to treat hard-to-reach areas, an aerosol spray might be the best option.
OdorThe odor of a bed bug spray can impact your comfort during and after application. Some sprays have a strong chemical smell, while others are odorless or have a mild scent. If you are sensitive to strong odors or plan to use the spray in living areas, opt for an odorless or low-odor spray. Check product descriptions and customer reviews to get an idea of the spray's scent. If you prefer a more pleasant experience, choose a spray with a mild or no odor.